Bovine spongiform encephalopathy (BSE) Biochemistry homework help

    Introduction:
    Bovine spongiform encephalopathy (BSE) also known as mad cow disease is a worldwide problem. While the United States and many countries in the European Union have regulatory legislation in place to combat the spread of BSE many other countries do not yet have the ability to enact such regulations making the import and use of possibly tainted beef a health risk.
    You should compile your work for this task in a single document (e.g. Microsoft Word Google Document) that will include diagrams models text explanations and references. If a requirement asks for an explanation you should provide a written response in a narrative style (i.e. complete sentences rather than bullet points).
    Note: Multimedia presentations (e.g. PowerPoint Keynote) will not be accepted due to potential originality concerns.
    Note: Please save submission documents as *.doc *.docx *.rtf or *.pdf files. If you are using Google Documents you must save the file in *.pdf format and upload the *.pdf file.
    Scenario:
    As a specialist in biochemistry you have been asked to be part of a team that will assist a country that currently does not have regulatory legislation. You will help the other workers in understanding BSE at a chemical level. Because these workers are unfamiliar with the basic biochemistry concepts necessary to understand how BSE occurs you will need to include an overview of proteins.
    Requirements:
    A. Create an original model of anessentialamino acid (e.g. lysine threonine) that shows the atoms and bonds in both the backbone and the side chain.
    Note: Take a picture or screenshot of your completed model as evidence that you created it. You can include the picture or screenshot as part of your document or you can submit it in Taskstream as a separate attachment.
    B. Create an original diagram or series of simple diagrams with clear labels of the different levels of protein structure (i.e. primary secondary tertiary and quaternary).
    C. Create an original diagram or series of simple diagrams that demonstrates how a peptide bond is made through dehydration using a complete chemical equation.
    Note: A complete chemical equation includes the chemical structures of all reactants an arrow indicating the direction of the reaction and the chemical structures of all products.
    D. Create an original diagram or series of simple diagrams that demonstrates how a peptide bond is broken through hydrolysis using a complete chemical equation.
    Note: A complete chemical equation includes the chemical structures of all reactants an arrow indicating the direction of the reaction and the chemical structures of all products.
    E. Explain thefourforces (i.e. bonds or interactions) that stabilize a proteins structure at the tertiary level.
    F. Explain how bovine spongiform encephalopathy (BSE) occurs at a molecular level by doing the following:
    1. Explain the role of prions in BSE includingeachof the following:
    how prions are formed
    the connection between misfolding and aggregation
    how prions lead to the disease
    2. Explainonepossible role of a chaperone protein in BSE includingeachof the following:
    how chaperones normally act in the cell
    how a chaperone protein can contribute to BSE
    3. Recommendtwoways that a country without regulations in place can decrease the risk of transmitting the prion involved in BSE (e.g. feeding practices animal disposal).
    G. When you use sources include all in-text citations and references in APA format.

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