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    Does the disorder affect water balance? [consider diffusion, osmosis, hydrostatic pressure, hormonal control]

    Does the disorder affect the metabolism of any electrolytes?

    Does an imbalance in water, electrolytes or acid-base affect the disorder?

    Does the disorder affect any endocrine hormones? Conversely, do any endocrine hormones affect the disorder?

    Does the disorder or treatment of the disorder affect glucose metabolism?

    Are any structures or functions of the gastrointestinal tract affected by the disorder? [include GI secretions in this discussion]

    Does the disorder or treatment of the disorder affect GI motility?

    Does the disorder affect metabolism of carbohydrates, proteins, fats, water, minerals or electrolytes?

    Does the disorder or treatment of the disorder affect liver or pancreas function? Does altered liver or pancreas function affect the disorder?

    Does age affect the disorder?

    Does the disorder affect the structures or functions of the reproductive tract?

    Are any special senses affected by the disorder? Does an alteration in any of the special senses affect the disorder?

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